M20 Seq^®

Differ from traditional single-cell sequencing technologies using oligo dT capture technology (only capturing the 3' or 5' end of mRNA), “M20 Seq” can capture the full-length of RNA based on random primer. In addition to detecting gene expression abundance, it also allows detection of gene mutations, gene fusions, copy number variations, non-coding RNA, alternative splicing, and other features, expanding the application of single-cell sequencing technology in clinical oncology testing.

Based on random primer principle, “M20 Seq” does not require cell viability, making it applicable for single-cell detection of fresh tissue, frozen tissue, and even for formalin-fixed paraffin-embedded (FFPE) samples. This advancement surpasses limitations of sample types, time constraints, and geographical boundaries, making it particularly suitable for centralized laboratory testing.

Not limited to the Poly(A) structure of RNA, our technology is versatile for single-cell detection in a wide range of organisms, including eukaryotes such as humans, animals, plants, as well as prokaryotes such as bacteria.

Our technology substantially boosts the number of captured cells, scaling up to millions.

Based on random primer principle, our technology offers multiple capture opportunities for a single RNA molecule, resulting in a substantial enhancement of genes detection in single-cell sequencing.

Excellent detection results have been attained on both droplet-based and microwell-based platforms.